When you arrive in Chennai, you will feel as if you have another hometown in South India. People here don't care what religion you practice, where you're from, or anything else. Everyone will be engaged with their work. You will find it difficult to find a friend zone once you are settled because you do not like to leave the city.
It makes no difference where you study or what you study in college, it all depends on what you learn. Loyola is one of India's most well-known and oldest colleges, so you don't need to worry so much.
Now talk about some challenges you may face here:
The language barrier is the only thing you need to overcome. By doing that you will be able to adjust with the culture very easily.