IIT Guwahati is safe not only for South Indians but for every student of the college. The campus is very beautiful and the serene ambiance attracts many across the country. There is no reason to feel insecure here. If it’s the Hyderabad people you are worried about, lay your worries to rest because they are the most friendly you will find.
There is no impartial attitude towards students from any state and professors treat every student equally. Despite the language barrier, you can see great harmony between the students as they can often be seen playing together.
You can find diverse peer groups here and the love for Engineering and nature can be seen as the binding factor between them. Parents of certain children often hesitate from sending their children to the Northeast but trust me after a few months you will think of IIT Guwahati as your home, such is its charm.